Missouri

Businesses For Sale in Missouri

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Baked Goods Niche with Management in Place #1004

Saint Louis, MO

This acquisition opportunity represents multiple franchise locations in the baked goods niche, strategically positioned in a high-growth region within the US. One of the locations is the top...

$4,100,000

$4,100,000

Cash Flow: $1,445,416

Award Winning, Turn-Key Staffing Franchise For Sale

Franklin County, MO

Well established (1998), well known, award winning office; top staffing company in the area; brand name recognition; ISO certified; highly profitable; loyal, long term clients; well trained,...

$600,000

$600,000

Cash Flow: $400,000

Legacy Family Plumbing Company with Real Estate

Saint Louis, MO

Well established Plumbing Company founded 100 years ago. This is a unique opportunity to acquire a well established plumbing company with a loyal customer base in both residential and commercial...

$2,750,000

$2,750,000

Cash Flow: $418,121

Profitable Print Shop!

Saint Louis, MO

Profitable Print Shop providing for Basic to Specialized Printing needs in a Great location....

$835,000

$835,000

Cash Flow: $326,745

Breakfast Cafe for Sale Fully Equipped Ready for New Owner

Kansas City, MO

Step into an outstanding opportunity to establish your own concept with this second generation Breakfast Cafe for Sale in Missouri. Designed for flexibility and growth, this well equipped restaurant...

$80,000

$80,000

Beloved Own a Piece of St. Louis Dining History #1003

Saint Louis, MO

St. Louis City Iconic Restaurant – Business & Real Estate Opportunity! Here’s your chance to own one of St. Louis’s most iconic and beloved restaurants. With the current owner retiring, this...

$1,100,000

$1,100,000

Cash Flow: $455,273

Retail Scooters

Missouri

Family-owned retail scooter business in Southwest Missouri for sale. Serving the region for years, this business has built a strong reputation as a trusted transportation alternative - offering...

$299,000

$299,000

Cash Flow: $167,961

Independent Auto Care Center - $175k - $217k SDE

St. Louis County, MO

PRICE REDUCED - EXCELLENT GROWTH OPPORTUNITY. POSSIBLE ABSENTEE OWNERSHIP. 50 year old general auto repair center. 2024 Sellers Discretionary Earnings exceeded $175,000 ($217,000 if real estate is...

$359,999

$359,999

Cash Flow: $175,135

Profitable Daycare & Early Education Center #1000

Saint Charles, MO

Well-established, growing childcare center with strong community reputation and consistent annual growth. Prime location with ample parking, expansive grounds, and a facility designed specifically for...

$145,000

$145,000

Cash Flow: $32,444

Secure Data Processing Business #998

Saint Louis, MO

This established, U.S.-based data and document processing operation offers a rare opportunity to acquire a fully scalable, compliance-driven business with long-term client relationships across...

$325,000

$325,000

Cash Flow: $243,358

Privacy Fencing & Skilled Trade Business

Springfield, MO

From custom decks and staining to framing, fencing, and odd jobs, this business has built a reputation for delivering quality work that lasts. 2025 is already shaping up to be the strongest year yet,...

$175,000

$175,000

Cash Flow: $124,000

Unique Bar in St. Charles

Saint Charles, MO

This bar is located just off a major highway with great visibility from the street. This establishment has been serving unique beer options for well over a decade and provides the most unique...

$125,000

$125,000

Nora Mental Health Franchise

Manufacturing Industrial Machinery Shop

Saint Louis, MO

Manufacturing Industrial Machine Shop providing Design, Implementation, Production, Custom Fabrication as well as Small Batch Production and Welding....

$360,000

$360,000

Cash Flow: $144,770

Highly Profitable Trucking Company ***SBA Approved***

Saint Louis, MO

Get ready for an exciting opportunity! SBA Approved St. Louis trucking company has been a pillar of superior customer service for over 20 years, proudly delivering on every promise and handling an...

$2,200,000

$2,200,000

Cash Flow: $311,678

Jennifer Smith Broeckling, MBA, BCI, CMAI

Murphy Business Sales

Serving Cape Girardeau County, MO

Most people don't know where to begin when it comes to buying or selling a business. We guide clients through the complicated process so they get to the closing table successfully. Our mission: To be an ethical business brokerage firm that sets buyers, sellers, and their businesses up for success in the next chapter of their lives. Our core values: 1. Integrity 2. Honesty 3. Learning 4. Accuracy 5. Adaptability Our vision: We are known as one of the most ethical, capable, and skilled business brokerage groups in the country who truly care about people and their deals.

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Luxury Wellness Studio/Spa

Saint Louis, MO

Step into ownership of a modern, state-of-the-art wellness studio built for today’s growing demand in health, recovery, and performance optimization. This turnkey business delivers innovative,...

$705,000

$705,000

Cash Flow: $197,000

Countertop / Custom Surfaces Fabricator & Installer $6MM in Revenue

St. Louis City County, MO

A well-established countertop fabrication and installation company with a stellar reputation for quality craftsmanship, customer service, and timely project completion. Servicing residential,...

$4,500,000

$4,500,000

EBITDA: $815,000

Very Profitable Residential Care Facility

Greene County, MO

Highlights of Business • Business is well established (40+ years) and well run with experienced, capable, dependable employees • Business model is a very successful niche focus • 2025 was best year...

$389,000

$389,000

Cash Flow: $190,425

Two Established Auto Repair Facilities in Key Locations #994

Saint Louis, MO

Imagine owning two thriving auto repair shops without the daily grind of running them yourself. These aren't just any repair facilities - they're established operations in Saint Louis with stellar...

$650,000

$650,000

Cash Flow: $289,197

Retail Sales, Service, Home Improvement Business #992

Saint Louis, MO

This is a rare chance to acquire a highly successful, long-standing retail sales and service enterprise with a proven track record of profitability and community trust. Located in the heart of...

$995,000

$995,000

Cash Flow: $450,898

Digital Advertising Franchise - Scalable, High-Margin Model #991

Saint Louis, MO

An exciting opportunity exists to acquire a fast-growing digital advertising franchise specializing in indoor digital displays across high-traffic venues. This business leverages a unique and proven...

$125,000

$125,000

Cash Flow: $72,674

Profitable Sales & Service Business with Prime Location! #990

Saint Charles, MO

This established sales and service enterprise represents a compelling acquisition opportunity, having operated continuously for over two decades with demonstrated profitability and market stability....

$750,000

$750,000

Cash Flow: $294,945

2 Truck fleet nets 5k-8k+ Monthly Guaranteed

Thriving Busy Restaurant in a Prime Location #986

Saint Charles, MO

Own a well-established restaurant located in one of the most desirable areas in St. Charles County. This successful, fully staffed restaurant is beautifully maintained and well-positioned for...

$350,000

$350,000

Cash Flow: $119,129

Used Car Dealer & On-Site Automotive Repair Shop #985

Columbia, MO

Recent New Price! An independently owned used car dealership with an on-site repair shop, serving Columbia and the surrounding area. The business focuses on offering reliable pre-owned vehicles and...

$475,000

$475,000

Cash Flow: $186,692

Scalable Home Service Company #983

Saint Louis, MO

Imagine stepping into a thriving junk removal business that's already winning hearts across the greater St. Louis area. You'll inherit a company with stellar reviews and a customer base that keeps...

$320,000

$320,000

Cash Flow: $183,049

Lively Bar & Grill with Gaming, Music, Patio & Dance Floor!

Jefferson County, MO

This bar and grill is all about great food, cold drinks, and unforgettable nights. Guests love the gaming action, live music on the big stage, and dancing on the spacious floor — plus the patio is a...

$300,000

$300,000

Cash Flow: $148,800

23 FedEx Ground Routes - Columbia, MO - Seller & Vehicle Financing

Sedalia, MO

Asking Price: $1,300,000 in outright cash, plus $625,000 in estimated possible vehicle financing, plus $500,000 in seller financing (Total Purchase Price: $2,425,000). FedEx Ground Routes for Sale:...

$2,425,000

$2,425,000

Cash Flow: $853,691

10 FedEx Ground Routes - Columbia, MO - Seller & Vehicle Financing

Sedalia, MO

Asking Price: $800,000 in outright cash, plus $275,000 in estimated possible vehicle financing, plus $225,000 in seller financing (Total Purchase Price: $1,300,000). FedEx Ground Routes for Sale:...

$1,300,000

$1,300,000

Cash Flow: $417,074

Established Cleaning Business

Missouri

Don't miss this chance to own a thriving, reputation-driven cleaning business in Southwest Missouri! Established in 2018, this BBB-accredited A+ rated company has become a go-to provider for...

$120,000

$120,000

Cash Flow: $81,393

Price Reduced: Profitable Mobility Franchise

Missouri

This well-established mobility equipment business is part of a trusted national brand, offering the advantage of name recognition, proven systems, and ongoing corporate support. The company provides...

$177,000

$177,000

Cash Flow: $34,949

Profitable Commercial Services Company

Missouri

This profitable commercial services company located in the Kansas City metro area presents an exceptional opportunity for an acquirer seeking a well-run, scalable platform in the facility maintenance...

$4,700,000

$4,700,000

Cash Flow: $1,034,710

Exclusive Garage Living Territory Available – Join a Growing Brand

Chesterfield Established Flooring Sales and Installation Business

Chesterfield, MO

Transform your entrepreneurial vision into reality with this established East Nashville flooring franchise that delivers immediate cash flow and long-term wealth building opportunities. You'll step...

$225,000

$225,000

Biggies Restaurant is looking for a Strategic Partner

Saint Louis, MO

Biggies Restaurant has been in business for over 30 years and they are looking to take on a Strategic Partner to grow and expand the current operation. They are looking for someone that has vision,...

$1,800,000

$1,800,000

Cash Flow: $263,305

A Breath of Fresh Air - Profitable Duct Cleaning Company For Sale!

St. Louis County, MO

Looking for a business that blows away the competition? This well-established, confidentially listed franchise specializes in air duct cleaning and HVAC restoration services, offering a proven model...

$599,000

$599,000

Cash Flow: $218,758

Medical Sales and Service Business

Saint Louis, MO

***SBA Pre-Approved*** This business has been helping individuals with limited mobility for 20+ years. They have multiple locations in order to service a larger customer base....

$2,640,000

$2,640,000

Cash Flow: $603,939

Profitable Missouri Restaurant with Real Estate, 90 minutes from KC

REAL ESTATE INCLUDED

Livingston County, MO

Thriving Livingston County, Missouri Restaurant for Sale, just 90 minutes Northeast of Kansas City, is serving up serious sales and profits! With in annual sales exceeding $2 Million and Owner...

$1,475,000

$1,475,000

Cash Flow: $269,319

REAL ESTATE INCLUDED

Liquor, Tobacco, Lottery, & Convenience Product Store #981

Saint Louis, MO

This is a prime opportunity to acquire an easy-to-run liquor and convenience store ideally situated in one of St. Louis County’s busiest retail corridors. Well known for its extensive inventory of...

$120,000

$120,000

Best in Class Custom Home & Craftmanship Remodeling Construction #980

Saint Louis, MO

For over 80 years this company has built an unwavering reputation among high-net-worth customers for renowned craftmanship. Construction includes new custom homes, extensive additions, and kitchen and...

$2,000,000

$2,000,000

Cash Flow: $1,057,874

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Commercial Kitchen Equipment Distributor & Manufacturer #979

Saint Louis, MO

This successful company has a proven track record selling a broad range of equipment for commercial kitchens. They have many long-term customers, a strong regional reputation and fourteen loyal...

$1,800,000

$1,800,000

Cash Flow: $552,083

Profitable Pool Servicing Business for Sale – Warren County, MO

Warren County, MO

Here’s your chance to own a well-established, highly reputable Pool Servicing Business located in beautiful Warren County, Missouri. With over a decade of successful operation, this business has built...

$455,000

$455,000

Cash Flow: $171,603

35 Year Proven System With A Franchise Guarantee

Specialty Home Infusion Agency Serving Kansas

Missouri

This Medicare-certified home infusion agency has been delivering complex, high-acuity treatments directly to patients’ homes since 2015. Licensed for specialty nursing, the company serves the greater...

$400,000

$400,000

Auto Repair & Tire Distribution Co.

Clayton, MO

Scope of Services: The company specializes in tire sales, routine maintenance, and related automotive services. Inventory levels were recently scaled to more than 10,000 units, supporting robust...

$595,000

$595,000

EBITDA: $486,435

Global Medical Device Manufacturing and Distribution

Saint Louis, MO

Here is a chance to jump into the medical device market with a proven product line for minimal cost. They have proven strongholds in the market space with multiple products and a sales team that...

$4,500,000

$4,500,000

Towing Company

Saint Charles, MO

This towing company has been around for over 15 years and serves a large area that covers St. Charles, St. Peters, St. Louis, O'Fallon, Cottleville, Earth City and Creve Coeur just to name a few. They...

$625,000

$625,000

Cash Flow: $135,573

St. Charles HVAC Company

Saint Charles, MO

This HVAC company has been servicing the St. Charles area since 1975. This family owned company is looking to hand the business over to a new owner as health concerns have taken its toll on the family...

$150,000

$150,000

Storage Business on 6 acres for Sale

Saint Charles, MO

Opportunities like this do not come around often! This business sits on 6 acres in St. Charles and is located just a couple of miles off the highway giving easy access for customers. Real Estate is...

$2,750,000

$2,750,000

Drive Away with Profits- Auto Lot With In House Financing for sale

St. Louis City County, MO

This well-established pre-owned auto dealership has been operating under the same ownership for more than 25 years! Located in a high-traffic area, the business has built a loyal customer base by...

$3,500,000

$3,500,000

Cash Flow: $701,622

Well-Established Auto Repair Shop for Sale

Saint Louis, MO

Take the wheel of a long-standing, highly reputable auto repair shop serving the St. Louis metro area for several decades. 6 bays, skilled experienced technicians, location with strong traffic count....

$1,350,000

$1,350,000

Cash Flow: $236,936

Leading eLearning & On-Demand Training Platform #973

Saint Louis, MO

Step into the future of professional training with the nation’s leading subscription-based video and eLearning platform for law enforcement. This highly respected, reality-driven training company...

$99,000

$99,000

Upscale Med Spa in Affluent Ski Town #971

Saint Louis, MO

Profits are way up! Don’t miss your chance to own a Thriving Med Spa in a Premier Resort Location in Colorado. This is your chance to own a highly successful and profitable med spa with exceptional...

$750,000

$750,000

Cash Flow: $189,239

Highly Profitable Specialty Retail Business #969

Saint Louis, MO

An exceptional opportunity to acquire a well-established, thriving specialty retail business with a loyal and growing customer base. This business has built a stellar reputation over the years for...

$99,000

$99,000

Cash Flow: $73,579

Buy a Small Business in Missouri

Missouri is nicknamed the “Show-Me State,” and it isn’t hard to understand why. This midwestern state has plenty to show residents and tourists alike, including the beautiful outdoors and plenty of city attractions. Two major cities, St. Louis and Kansas City, fill the need for sports, art, and shopping, while other areas of the state offer outdoor entertainment by virtue of camping, hiking, fishing, and more. With a population of over six million, which continues to climb, it’s no surprise that there are hundreds of options if you are in the market to buy a business in Missouri.

The state of Missouri has a diverse economy and nearly endless choices of businesses. Some of the most popular industries in this midwestern state include energy solutions, information technology, advanced manufacturing, and health sciences. As the third most diverse economy in the country and boasting a central location, there’s very little you won’t find in this gem of a state. Missouri is number one when it comes to food companies, animal health research, and more. For a business owner who appreciates the peace and quiet of a growing state with potential for many outdoor excursions, you can’t beat Missouri. 

Some of the current Missouri businesses for sale include restaurants, construction companies, gas stations, and campgrounds and RV parks. If none of those are to your taste, plenty of other options are available if you have an idea of what you are interested in based on your talents and hobbies.Regardless of industry, the business you choose to build in Missouri will bring you to a great location in the middle of everything.