Greenville County, SC

Businesses For Sale in Greenville County, SC

Showing 104 results sorted by
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Main Street Commercial | Business & Real Estate Package

REAL ESTATE INCLUDED

Piedmont, SC

This offering represents a rare opportunity to acquire a well-established lawn mower sales and repair business along with the underlying real estate in a highly visible Main Street location in...

$249,999

Cash Flow: $100,000

4

$249,999

Cash Flow: $100,000

REAL ESTATE INCLUDED

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Most Exclusive Cigar and Martini Lounge in Greenville SC

Greenville, SC

This premium cigar lounge and martini bar is a well-established, upscale destination offering an exceptional customer experience. Featuring a large walk-in humidor, full-service bar, multiple lounge...

$450,000

14

$450,000

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Owner Op'd Vape Store - Inventory Included - Highly Motivated!

Greenville County, SC

Owner Operated Vape and Tobacco Business on one of the Busiest Roads in Greenville County. Your Business Revenue made $290k in Sales in 2025. You want to be a Business Owner with a Business that...

$150,000

$150,000

Cash Flow: $93,421

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10 Years Strong Thriving CycleBar Franchise for Sale

Greenville County, SC

This is an established, highly successful CycleBar location that has been in business for 10 years, profitable from day one, and now contains a 30,000-person email database and 300 loyal members....

$99,000

$99,000

Cash Flow: $130,000

long established cleaners

Greenville County, SC

Dry Cleaners been established for many years, sits in the heart of booming town. The cleaners has been around for more than 30 years and the go to for town members for years....

$250,000

$250,000

Greenvilles only all Halal and Kosher restaurant

Greenville County, SC

Greenville first and ONLY 100% halal and kosher restaurant. Serving mouth watering dishes like 100% authentic lamb gyros , Lamb chops, chop cheese, wings and a whole wide range of menu items including...

$275,000

$275,000

Subway Franchise for Sale with Trained Staff!

Greenville, SC

Own a proven sandwich concept in thriving Greenville with this Subway Franchise for Sale. Step into a turnkey, second generation restaurant that is fully built out with utilities and permits in place,...

$175,000

$175,000

SC Bike Shop for Sale

Greenville County, SC

Established South Carolina Bike Shop - Turnkey Operation in Growing Market This well-established bicycle retail, service, and rental business has been serving Greenville County since 2014, generating...

$450,000

$450,000

EBITDA: $60,000

Authentic wing and fried rice

Greenville County, SC

This authentic mom and pops has been operations for more than 20 years in same location. Serving authentic wings and fried rice, has a couple additional menu items but limited. With very good rent!!...

$115,000

$115,000

Seller Financing Available! Restaurant for Sale Ready to Operate!

Greenville, SC

This Restaurant for Sale presents an excellent opportunity for an experienced owner/operator seeking a fully equipped, independent space with no franchise restrictions. Spanning 2,850 square feet and...

$199,000

$199,000

Own This SC Restaurant Real Estate on Over 7 Acres!

REAL ESTATE INCLUDED

Greenville, SC

This Restaurant Real Estate for Sale near Greenville, SC offers a rare opportunity to own both the business and the property it occupies. Sitting on approximately 7.41 acres and offering around 4,600...

$1,500,000

$1,500,000

REAL ESTATE INCLUDED

Restaurant for Sale with Real Estate Outdoor Seating!

REAL ESTATE INCLUDED

Greenville, SC

Looking to own a Restaurant for Sale with Real Estate? This opportunity is ideal for a hands on owner/operator ready to take the reins of a fully equipped restaurant space. Offered by We Sell...

$3,900,000

$3,900,000

REAL ESTATE INCLUDED

Profitable High-Volume Freight & Logistics Business

REAL ESTATE INCLUDED

Greenville County, SC

This Greer, South Carolina-based freight and logistics operation has built a high-volume, multi-service transportation platform with deep roots in the industry and over two decades of proven...

$5,450,000

$5,450,000

Cash Flow: $600,000

REAL ESTATE INCLUDED

Paint The Town!

Greenville County, SC

Paint The Town! - Line Striping Business for Sale Established franchise opportunity in the specialized line striping industry, serving Greenville, Spartanburg, and Anderson County, SC as well as...

$300,000

$300,000

ALL glass tint

Greenville County, SC

Well known tint..auto...residential and commercial...

$275,000

$275,000

Daniel Ober

First Choice Business Brokers

Serving Greenville County, SC

First Choice Business Brokers is one of the largest business sales organizations in the U.S., listing over $7.5 Billion in businesses for sale since our foundation in 1994. First Choice Business Brokers specializes in business sales across all industries with transaction sizes from approximately $50,000 to $50 million. First Choice Business Brokers assists business owners in selling their businesses by locating and matching them with a buyer and managing the entire sales process. Additionally, we also work with business buyers to find the right business that meets their purchase criteria. With several offices located throughout the U.S., we have sold thousands of businesses, of all types, confidentially and efficiently through our vast buyer networks.

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Established coffee shop with a great atmosphere and Location

Greenville, SC

An established coffee shop for sale in great location. Cozy environment and great repeat customer base. Owners are retiring after 20 years in the industry....

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$116,000

$116,000

Well Established Gourmet Dessert Vendor

Greenville County, SC

If you are looking for a proven, highly flexible business with exceptional growth potential, this is an excellent opportunity to be your own boss! Operating successfully for 11 years, the owners have...

$399,000

$399,000

Cash Flow: $129,539

Liquor Store. Very Busy Area

Greenville County, SC

In South Carolinas busiest street...

$400,000

$400,000

Commercial building in next phase booming Greenville, SC

REAL ESTATE INCLUDED

Greenville County, SC

Building sits on .20 acre lot with dry cleaning equipment. In a very busy main rd that connects two major booming towns literally minutes away. The building has a 3 bedroom and 1 and half baths...

$850,000

$850,000

REAL ESTATE INCLUDED

Booming Industry: Essential, Professional Nannies and Child Care

Greenville, SC

Interested in a “high demand” business model that combines high-margins, recurring revenue, professional nanny services, with matching software and hiring systems . Here's a concise overview: Business...

$115,000

$115,000

Cash Flow: $201,000

3 Yr Authentic Italian & Pizza $800K Sales & Strong Profit.

Greenville County, SC

Are you ready to sink your teeth into a delicious opportunity? Look no further than this well-established Italian Restaurant located in Upstate South Carolina. With over 30 years of excellence in the...

3

$450,000

$450,000

CNC Machining - Turning & Milling Established 20 years

Greer, SC

This CNC machining company has been established for over 20 years. The company has a number of long term, high quality customers in the local area. They supply precision parts primarily to the...

$2,950,000

$2,950,000

Cash Flow: $926,690

Under Contract - HVAC Biz with Contracts - Seller Finance

Greenville County, SC

Deal Structure: Price $1,318,000, Down Payment of $700,000 for qualified Buyers with $618,000 Seller Note. Seller is willing to stay on as Technician. Own this well-established HVAC company with a...

$1,318,000

$1,318,000

Cash Flow: $476,558

Seller Note - Machine Shop with Long-Standing Relationships

Greenville County, SC

Specializing in high-quality metal fabrication and CNC, this Greenville County Business is an amazing opportunity to own an established operation with a robust and long-standing reputation in...

$295,000

$295,000

Cash Flow: $94,460

Under LOI: Growing and profitable home cleaning company for sale

Greenville County, SC

The company was started from scratch in 2017. As a result the company was set up from the start to be as turn key as possible. The company offers home cleaning services and has a large base of stable...

2

$850,000

$850,000

Cash Flow: $275,000

Unique High Traffic Dining Concept

Greenville, SC

PRICED TO SELL; One of Greenville's most unique food venues with a huge customer base that continues to grow. Seller has other business investment opportunities that needs his full attention. The...

$249,000

$249,000

Cash Flow: $107,714

Ready To Go Restaurant for Sale! Owner Financing Available!

Greenville, SC

This Ready To Go Restaurant for Sale in the bustling area of South Carolina offers an exceptional opportunity for an experienced operator seeking a fully equipped, turn key space. Located in a high...

$179,000

$179,000

15 Yr $450K Revenue, $83K SDE Pressure Wash Co-4 staff

Greenville County, SC

LENDER PRE-SCREENED with 10% BUYER EQUITY. Looking for a solid business that practically rinses and repeats? This 15-year-old pressure washing company in Upstate South Carolina is a shining...

$297,382

$297,382

Cash Flow: $73,808

Greenville Pizza Franchise for Sale! Growth Potential Awaits!!

Greenville, SC

Step into ownership with this fully equipped Pizza Franchise for Sale in Greenville, SC, offering a fantastic opportunity for an entrepreneurial operator ready to take charge of a proven, turn key...

$285,000

$285,000

Automotive Repair Shop In Great Location

Greenville County, SC

Structure of Sale: -Sale price: $600,000 -Downpayment: $200,000 -Seller financing: $400,000 -Terms: 9.5%, amortized x 10 years, balloon in 5 This well-established automotive repair business has built...

$600,000

$600,000

Cash Flow: $200,401

Vending business and location

Greenville, SC

ESTABLISHED ICE AND WATER VENDING BUSINESS - GREENVILLE, SC This turnkey ice and water vending operation features the premium Everest VX ice vending machine, recognized for its superior reliability...

3

$40,000

$40,000

Cash Flow: $26,000

Modern Greenville Clinic with Loyal Patients

Greenville, SC

This well-established, neighborhood Urgent-Care Clinic in Greenville, SC is an attractive acquisition opportunity for a healthcare entrepreneur, physician group, or strategic purchaser. On a mission...

5

$395,000

$395,000

Mathnasium Learning Center for Sale, SC (2433107)

Greenville, SC

With over 1000 centers – and more opening each week – Mathnasium is rapidly growing in neighborhoods around the world. That’s because we are passionate about what we do. It’s also because our...

2

$50,000

$50,000

Turn Key Restaurant for Sale in Growing Spartanburg Suburb!

Greer, SC

This Restaurant for Sale presents a rare opportunity to own a fully equipped, turn key space in one of the Upstate's most promising and fast developing markets. Spanning approximately 1,200 square...

$159,000

$159,000

Upscale Mobile Custom Suits/Blazers Biz w/70% Net Profits!

Greenville, SC

Imagine running your own upscale mobile tailoring business where you're bringing premium custom clothing directly to high-end clients in the thriving Greenville-Spartanburg area. This isn't just any...

$54,000

$54,000

Semi-absentee | Niche, Different, Moving business!

Greenville, SC

We focus on making moving a better experience for the customer! We bring a silly, lighthearted, and fun attitude to the moving business. We give the customer dinner the night before! We have even been...

$170,000

$170,000

Innovative High-Margin Window & Exterior Cleaning Business!

Greenville, SC

This window and exterior cleaning business was founded on the idea of world-class service at a fair price. We stand out by doing three simple things… We show up on time. We do what we say we’re going...

$250,000

$250,000

Cash Flow: $225,000

Profitable Downtown Greenville Restaurant

Greenville, SC

This is a rare opportunity to acquire a well-established, highly profitable downtown restaurant in the heart of Greenville, one of the fastest-growing and most desirable small cities in the Southeast....

$595,000

$595,000

Cash Flow: $233,000

Greenville NY Style Pizzeria in a Fantastic Location

Greenville, SC

Turn-key NY-style pizzeria in a prime Greenville location. Bring your concept to one of the fastest-growing and most desirable markets in the Southeast. This fully equipped New York–style pizzeria...

$149,000

$149,000

Established and Popular Tattoo Parlor for Sale

Powdersville, SC

Established, Award-Winning Tattoo Parlor in Prime Upstate SC Location Relentless Tattoo is a fully built-out, high-end tattoo parlor located in one of the most visible commercial corridors in Upstate...

$159,000

$159,000

Cash Flow: $125,000

Bruce Johnson

VR Business Sales | M&A | Commercial Realty

Serving Greenville County, SC

Established in January 2007, we serve our clients by providing confidential and highly professional representation in all aspects of the sale process including valuation of the business, targeted marketing of the business, and negotiation of the transaction with qualified potential buyers. We are consistently recognized as one of the top VR offices in the US based on the volume of successfully completed transactions. Our mission is to help business owners and franchisees successfully sell their businesses at the right time and for the best possible price under prevailing market conditions. At the same time, we enable qualified entrepreneurs to successfully purchase a business that meets their professional and lifestyle objectives. We are proud to have trust, honesty and integrity as fundamental values in our process. Our network of business intermediaries work together to not only complete the sales transaction, but also to serve as an advocate for our clients throughout each phase of the transaction.

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Greenville Restaurant with Parking

Greenville, SC

Discover a unique opportunity to own a charming freestanding restaurant in vibrant downtown Greenville, SC. This attractive property boasts rare private parking for 10 vehicles—an invaluable asset in...

$299,000

$299,000

Cash Flow: $65,000

Medical Spa & Body Sculpting Treatment Center In Greenville

Greenville, SC

This medical and beauty services clinic offers a complete range of anti-aging, detoxification, and aesthetic services, blending science and wellness in a luxurious setting. The sale includes all...

$339,500

$339,500

Cash Flow: $261,440

Profitable Greenville Multi Unit Franchises for Sale!

Greenville, SC

Own Two Multi Unit Franchises for Sale in Greenville, SC A Money Making Opportunity! For less than the cost of starting just one new franchise, you can own two established locations in one of South...

$345,000

$345,000

Cash Flow: $53,895

Established Turn Key DME Retail with Service and Rental Incomes

Taylors, SC

Retail Durable Medical Equipment specializing in Scooters, Powe Chairs, Wheel Chairs, Knee Scooters, Rollators, bathroom equipment, ramps, including service, rentals, and repairs....

$125,000

$125,000

Cash Flow: $52,000

Reputable Home Care & Assistance Agency – Diverse Client Services

Greenville, SC

With a commitment to compassionate, dependable care, this agency provides non-medical assistance to seniors, individuals in recovery, and those living with chronic conditions. Its approach is built on...

$249,000

$249,000

Cash Flow: $209,211

Prosperous Plumbing And HVAC Company Running Semi Absentee

Greenville, SC

This plumbing company doesn't just handle pipes... they can fix HVAC systems too! This is a great 2-in-1 deal that gives a buyer the best of both worlds. Handle both pain points for homeowners by...

$674,900

$674,900

Cash Flow: $243,806

Painting Company with Systems for Scale

Greenville, SC

Imagine stepping into a thriving painting business that's already built a solid reputation. You'll find yourself at the helm of a professionally branded operation that serves both homeowners and light...

$595,000

$595,000

Cash Flow: $260,000

Home Based Irrigation Business in South Carolina

Greenville County, SC

LISTING ID # 36064 This well-established home-based irrigation business has been proudly serving Upstate South Carolina for the past 24 years, specializing in new installations and repairs for...

$185,000

$185,000

Cash Flow: $110,000

Technology-Driven Sports Entertainment Venue

Greenville, SC

Imagine walking into your own upscale indoor golf and entertainment venue where cutting-edge simulator technology meets warm hospitality. You'll love how this business combines the excitement of...

$514,900

$514,900

Cash Flow: $172,348

Liquor Store - Great Location with High Traffic

Greenville, SC

Great liquor store for sale! A well-established liquor store in the thriving Greenville, SC area is now available for acquisition. This profitable business offers a diverse selection of wines and...

$220,000

$220,000

Cash Flow: $40,857