Health Care and Fitness Businesses For Sale in South Carolina

Start-up$400B Health & Wellness Market – Proven Model with Recurring Revenue

Stepping into the thriving health and wellness industry has never been more promising. This franchise opportunity, backed by over three decades of success and a global health conglomerate, offers...

$60,000

Start-upSenior PCA,Home Health & Hospice Care Franchise/$0 Fee Veteran Program

Auction

Value-Add Med Office With 14 Private Offices

Columbia, SC

Online auction: February 2-4, 2026

Off I-26, 10 miles from Downtown Columbia
Med office user-ready w/ 14 private offices

$125,000 starting bid

Starting bid:

$125,000

Auction

REAL ESTATE INCLUDED

Are you interested in a healthcare career? And if you are a veteran, transitioning military member, or spouse, we want to help you join our military-connected $0 Fee Veteran Program with no upfront...

$30,000

Start-upSenior PCA,Home Health & Hospice Care Franchise/$0 Fee Veteran Program

$30,000

Start-upRest Recovery Wellness (Ice Bath / Cold Plunge and Sauna Company)

Pioneering Health and Wellness License Opportunity We are the true one stop shop for wellness. We offer more tools and modalities then anyone in or around the market - COMPRESSION - PEMF - INFRARED...

$35,000

Well maintained Anytime Fitness gym. Profitable with absentee owner.

Easley, SC

I have been a franchisee with Anytime Fitness for roughly 7 years. I own multiple businesses, and have been scaling down over the past 2 years to narrow my professional focus, allowing myself more...

$275,000

Cash Flow: $30,000

Top Area Cycling Studio - Growing Community and current Free Rent

Pickens County, SC

Own this Incredible Cycling Studio with Top of the Line Equipment, Growing Community of Members, and Unbeatable Location! Since 2023, this Business has been building a Community of Loyal Members who...

$195,000

Cash Flow: $14,765

FranchiseHomewell Care Services

Available in South Carolina

An Opportunity Like None Other: Where Personal Fulfillment Meets Financial Success

$50,000

$50,000

Ultrasound Studio & Boutique

Horry County, SC

Turnkey Ultrasound Studio + Brand Revenue Extension | Dual Revenue, Prime Location, Growth-Ready! Step into ownership with confidence—this fully operational ultrasound studio and semi passive revenue...

$315,000

Cash Flow: $101,988

Multi-Unit Franchise—Fitness Related

Horry County, SC

Turnkey opportunity to acquire 3 established fitness-related business locations serving the highly desirable Myrtle Beach market. As part of a respected national brand with nearly 400 locations and...

$790,000

Cash Flow: $235,000

Home Care Senior Services Tailored For Independence

Columbia, SC

Imagine owning a business that truly makes a difference in people's lives every single day. This established home care company has been serving the Columbia community for years, building an incredible...

$119,900

Cash Flow: $122,315

Modern Greenville Clinic with Loyal Patients

Greenville, SC

This well-established, neighborhood Urgent-Care Clinic in Greenville, SC is an attractive acquisition opportunity for a healthcare entrepreneur, physician group, or strategic purchaser. On a mission...

$500,000

Stretch Your Success: Turnkey Stretch Zone Studio for Sale in Aiken

Aiken, SC

Successful Stretch Zone franchise studio offering practitioner-assisted stretching services in the thriving Aiken, SC market. This turnkey operation generates $387,000 in annual revenue through a...

$70,000

Seth R. Blackburn

BridgeWorth & Associates

Serving Lexington County, SC

We specialize in the sale of existing businesses to qualified business buyers. From manufacturing, service, technology, retail, and all in between. We cater to many of our clients across the United States. Our confidential systems are ironclad and backed by non disclosure agreements. We also qualify all buyers and can get buyers qualified and financed so you don’t have to. We are relationship oriented, we are your support, we are knowledgable, we are persistent and we are trustworthy. We are both motivated by success and our number one priority, when it comes to BridgeWorth & Associates, is YOU!

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Dental Practice For Sale in Columbia, SC

Columbia, SC

Motivated Seller. Price Negotiable. Tremendous opportunity to purchase a well-established dental practice in a prime location with a loyal patient base. This practice has been providing quality dental...

$350,000

Cash Flow: $26,851

Nurse Staffing Agency

Charleston, SC

Well Established Medical Staffing Agency Connecting medical staff with health care facilities across the nation since 2020...

$249,000

Vitamin Infusion Business Growing Yearly

Horry County, SC

Fantastic opportunity to own one of the few businesses in the fast growing vitamin infusion sector. Weight loss packages, increase mind sharpness and energy are a few of the many options here at this...

$495,000

Cash Flow: $321,784

Asset SaleOnline Fitness licensing Trademark IP portfolio

Myrtle Beach, SC

Imagine owning a complete fitness brand portfolio without the headaches of managing staff, inventory, or real estate. That's exactly what you're getting here - pure intellectual property that's ready...

$89,900

Asset Sale

$89,900

Start-upOwn Your Future with an Elect Wellness Franchise, Start Changing Lives

Believe that God intelligently designed us? Maintain a great reputation in your community? Demonstrate a passion for natural health & fitness? Appreciate & pursue a servant-leadership style? Have the...

$23,500

FranchiseAssisted Living Locators

$23,500

Available in South Carolina

Empower Lives with Assisted Living Locators. Thriving Home-Based Referral and Placement Franchise. Discover Lucrative Opportunities for Business Success Today!

$50,000

$50,000

Start-upBody Sculpting- Licensed Med Spa business, Business professionals

Join the fastest growing mulit-billion dollar aesthetics industry with starting a body contouring med spa! You do not need to be a doctor or have a medical background. We teach you how to hire a...

Not Disclosed

Start-upPersonal Training Franchise - Low Investment, High Impact

Not Disclosed

Own a Personal Training Franchise That’s Low Investment, High Impact Revenue: Average $40,000+ per month (as disclosed in Item 19 of our FDD) Facility Size: ~1,275 sq. ft. per location Just You...

$25,000

World renowned fitness branded gym with yearly competitions.

$25,000

Horry County, SC

Fully equipped Crossfit gym, fully equipped with infrared sauna and cold plunge....

$225,000

Cash Flow: $75,000

Well established ophthalmology practice for sale

Columbia, SC

Well Established Ophthalmology Practice for Sale This thriving ophthalmology practice, established in 2006, represents an exceptional opportunity to acquire a well-positioned medical business in...

$425,000

Non-Medical Senior Home Care Company In Hilton Head

Hilton Head Island, SC

This local home care business enables us to make a valuable difference in people's lives. The book of business provides residual incomes from repeat customers. Over $1.8 million in invoices billed in...

$299,990

Cash Flow: $239,660

Charleston SC Chiropractic Practice for Sale

South Carolina

Exceptional Charleston chiropractic clinic with strong growth trajectory. Proven branding, EHR, and digital X-ray ensure a seamless transition, while modern systems and high-value equipment attract...

Not Disclosed

Cash Flow: $311,000

Not Disclosed

Cash Flow: $311,000

Long Standing Senior Care Services Company For Sale - Columbia

Columbia, SC

For Sale - This is a 22-year-established, internationally acclaimed “non-medical” senior care company. This home-based business has experienced continued growth, system-wide, year over year. Our...

$201,000

Cash Flow: $150,000

Established boutique Pilates studio in Greenville, SC

Greenville, SC

This fully equipped boutique Pilates studio offers a rare opportunity for a Pilates enthusiast to step into a turnkey business in a growing industry. Pilates is one of the fastest growing segments of...

$124,000

Profitable Non-Medical Home Care Business in Myrtle Beach

Myrtle Beach, SC

Imagine owning a thriving home care business that's been serving Myrtle Beach families for 12 years. This isn't just any business opportunity - it's your chance to make a real difference in seniors'...

$320,000

Cash Flow: $100,000

Well-Established Chiropractic Practice

Charleston, SC

This is an opportunity to acquire a long-established chiropractic practice serving the Charleston market since 1989. The practice has built a loyal patient base over decades and is well known in the...

$247,000

Cash Flow: $95,000

FranchiseMobility City

Available Nationwide

Mobility City is the nation’s premier repair, rental, sanitizing and retail sales company servicing wheelchairs, mobility scooters, power chairs, lift out chairs, hospital beds and other mobility products.

$100,000

Lexington Stretch Zone & rights to Florence

Sumter, SC

Columbia and Lexington stores are fully operational and staffed. Can sell both together or can break it up to only one store. Florence SC, I own the rights to the market, the store just needs to be...

$50,000

Specialty Footwear Store with Great Reputation

Horry County, SC

Specialty Footwear Store with Great Reputation This well-established specialty footwear retailer presents an exceptional opportunity in a thriving downtown district. Operating since 2022, the business...

$300,000

Cash Flow: $105,000

Reputable Home Care & Assistance Agency – Diverse Client Services

Greenville, SC

With a commitment to compassionate, dependable care, this agency provides non-medical assistance to seniors, individuals in recovery, and those living with chronic conditions. Its approach is built on...

$249,000

Cash Flow: $209,211

Two Location Optometry Practice For Sale

Lexington County, SC

This reputable optometry practice has been serving its community for over 40 years with two well-established locations in growing areas. The practice enjoys strong patient demand, booking appointments...

$500,000

Cash Flow: $225,668

South Carolina Medical Transport Business

South Carolina

Providing non-emergency medical transportation services to enhance accessibility to healthcare. The company serves a diverse clientele, ensuring patients receive timely and safe transit to medical...

$1,100,000

Cash Flow: $353,944

FranchiseFYZICAL Therapy & Balance Centers

Available in South Carolina

FYZICAL is the largest Physical Therapy franchise in the U.S. Their unique Balance & Fall Prevention Program differentiates them. No medical experience required.

$100,000

Established Boutique Fitness Studio for Sale in Fort Mill!

Fort Mill, SC

This high-energy functional fitness studio is fully equipped and turnkey, ready for a new owner to step in and start operating immediately. The studio offers group workouts combining strength, cardio,...

$100,000

Established Pediatric Therapy Clinic in Growing Charlotte Suburb

York County, SC

Available for purchase is a well-established, much-loved, community-based Pediatric Therapy Clinic offering physical, occupational and speech therapy to children from birth to age 18. This clinic...

$225,000

Cash Flow: $91,500

Established Home Care Franchise - Cleburne

Cleburne, SC

Cleburne branch office of an established home care agency for sale including current census. Highly sought after transferrable contract with the Department of Veterans Affairs (VA). Branch office...

$149,000

Pre-Revenue AI Powered Tech Business Focused on Mental Health Services

Charleston, SC

Proprietary AI powered therapist/client referral matching platform to establish and retain client-therapist relationships for therapeutic success available for sale. 6,500 vetted therapist members....

$1,800,000

High-End Wellness & Aesthetic Studio – Profitable & Turnkey

South Carolina

This is a confidential opportunity to acquire a high-end wellness and aesthetics studio in an affluent South Carolina coastal market. The studio offers a premium blend of massage therapy, non-invasive...

$245,000

Cash Flow: $110,000

Tim Dalton

Integra Business Brokers

Serving Greenville County, SC

Integra Business Brokers are a team of experts who offer professional services to their clients on all matters of Buying or Selling a Business, Mergers and Acquisitions, and business valuations. They assist Sellers in preparing and packaging their business for marketing. Buying a business or selling a business is not an easy undertaking, but with Integra Business Brokers you will not have to worry. They are fully licensed to deal in business brokerage and only employ trained and licensed brokerage professionals in full compliance with the South Carolina and Georgia Real Estate Commissions

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Premium Boutique Fitness Studio – Profitable, Established & Poised for

Charleston County, SC

This is a rare chance to acquire a thriving boutique fitness studio located in a high foot traffic end-cap space within one of the most desirable and affluent communities on the coast. With over 8...

$160,000

Cash Flow: $108,999

Established Physical Therapy Practice

Barnwell County, SC

Rare opportunity to acquire an established, profitable physical therapy practice in southern South Carolina with a loyal patient base and solid referral network. The practice offers comprehensive...

$328,000

Cash Flow: $110,000

Allergy & asthma practice in Myrtle Beach, South Carolina

Myrtle Beach, SC

For Sale: Established and highly successful allergy & asthma practice in Myrtle Beach, South Carolina, with average collections of $1,000,000. This practice provides a comprehensive range of allergy,...

$699,000

Established Home Care Business with Owner Financing

West Columbia, SC

Greater Colombia Market Home Care with OWNER FINANCING ACP Brands has been a leading home care service provider since 2004. Our owners provide non-medical, in-home care to keep their clients happy and...

$60,000

Highly Profitable (HIIT) Class and Personal Training Gym FOR SALE!!!!!

Myrtle Beach, SC

Well established franchise (HIIT) Fitness Class and Personal Training Gym available for immediate sale in the Myrtle Beach area. Built In clientele, a full staff or trainers and central location make...

$110,000

Cash Flow: $45,404

FranchiseHydrate IV Bar

Available in South Carolina

Hydrate IV Bar offers IV Therapy, Vitamin Injections and NAD+ IVs and Injections in a calm, spa-like environment, administered by an experienced RN.

$125,000

Turnkey Rehab Sports Clinic for Sale – Profitable and Scalable

York County, SC

This established rehabilitation-sports clinic is your opportunity to own a thriving rehab business, without the need for a license in South Carolina. Offering a comprehensive range of services...

$379,000

Cash Flow: $115,000

Franchised Non-Medical Home Care Business for Sale

Greenwood County, SC

This established franchised non-medical home care business provides essential in-home care services for seniors, allowing them to maintain independence and quality of life in the comfort of their own...

$365,000

Cash Flow: $105,902

Skilled and Non-skilled Home Health Care Service Franchise.

Greenville, SC

This is a caregiver franchise offering both skilled and non-skilled services. Established over 20 years ago, with a history of profitability. This business opportunity is SBA Pre-Approved with a low...

$149,000

Cash Flow: $93,354

Oral Surgery Practice Low Country, SC

South Carolina

Oral Surgery Practice Low Country, SC Listing ID 1456858 $1,085,000 Description Fantastic opportunity to purchase a well established Low Country Oral Surgery office in South Carolina. Located in a...

$1,085,000

Asset SaleFull Service Fitness Facility & Gym

South Carolina

Full-service fitness facility and gym for sale. Includes all equipment and FF&E. The facility is 26,000 SF and includes a large weight/ aerobics area, racketball courts, and a full gymnasium. It is...

$1,800,000

Asset Sale

FranchiseTruBlue

Available in South Carolina

Through senior modifications, home maintenance, handyman services, and ongoing maintenance programs, TruBlue franchisees have the opportunity to run a successful franchising business while making a difference in the lives of seniors and busy adults in their communities.

$50,000