Retail Businesses For Sale in South Carolina

Start-upWomen’s Boutique Franchise Opportunity.

Ella Blu presents an exceptional franchise opportunity in the upscale women's boutique market. Founded by Courtney Lyons, who has successfully owned and operated her boutique for over 22 years, this...

$50,000

Start-upTurn Key Packing & Shipping Stores, available starting at $75,000

Start your own profitable shipping and logistics business—affordably. At Qwik Pack & Ship, our mission is simple: empower entrepreneurs to own a proven, in-demand business without franchise fees or...

$37,500

Start-upPremium Vending Routes - Turn-Key Setup, Starting $39,900

READY TO OWN PROFITABLE VENDING ROUTES IN YOUR AREA? Stop chasing locations. We'll secure them for you. Premium vending routes available with brand new equipment, 5-year placement agreements, and...

$39,900

Start-upProfitable Cabinet Dealership – $250k+ Potential, No Royalties

Are you a successful sales leader, corporate professional, or veteran who has hit an income ceiling? Are you tired of building someone else's dream and ready to invest in a real, tangible asset for...

$250,000

Turn Key & Cash Flowing Vending Route w/ Latest Vending Technology!

Charleston, SC

ESTABLISHED VENDING MACHINE ROUTE - CHARLESTON METRO AREA This turnkey vending machine operation represents a fully established business opportunity in the Charleston metropolitan region, specifically...

$155,000

Cash Flow: $40,000

FranchiseLemon Tree Hair Salons

Available Nationwide

With over 40 years of experience we have worked to perfect our business model! We now have some of the most robust numbers in the hair care industry!

$100,000

$100,000

Hot Tub Store for Sale in South Carolina

Charleston County, SC

LISTING ID # 36421 Discover this well-established retail store specializing in hot tubs, swim spas, and saunas. While the business has been established for the last 8 years, the current owner has run...

$825,000

Cash Flow: $210,000

$130k Net Profit: Liquor Store/C-Store Combo

Anderson County, SC

Deal Structure: Store and Inventory Sold Separately - Store Price $275,000 with $75,000 Seller Note at 8% - Inventory is estimated at $200,000 for the Liquor Store and C-Store combined. Total Cost is...

$275,000

Cash Flow: $138,623

SC Bike Shop for Sale

Greenville County, SC

Established South Carolina Bike Shop - Turnkey Operation in Growing Market This well-established bicycle retail, service, and rental business has been serving Greenville County since 2014, generating...

$450,000

EBITDA: $60,000

High Margin CBD/Vape Store for Sale with no Competition

Beaufort, SC

Established CBD/Vape Store - Prime Beaufort Location This thriving smoke shop presents an exceptional opportunity for an entrepreneur seeking a profitable retail business in Beaufort, SC. Operating...

$300,000

High Volume Liquor Store

Greenwood County, SC

Liquor Store for Sale---Great Location & Steady Growing Income Established liquor store available for sale in a prime location. This store has a loyal customer base, excellent visibility, and...

$3,700,000

Greg Ponder

SMP Capital Partners

Serving Richland County, SC

SMP Capital Partners offer investment banking services to privately held businesses and business owners. We deliver efficient, trustworthy, and expert M&A services to businesses in the lower middle market up to $150m in enterprise value. With over 40 years of deep learned, real world deal experience, we understand how transactions work before they start and after they close. The investment banking professionals at SMP Capital Partners successfully bridge the gap between main street SBA business brokerage companies w/limited access to M&A and non-government underwritten capital markets, and the institutional investment banking firms who acquire businesses in the upper middle market.

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Established Specialty Market – Semi-Absentee and Strong Cash Flow

Lexington County, SC

This established specialty food market in the Lexington area offers a rare opportunity to acquire a well-run, semi-absentee business with strong and consistent cash flow. The operation has...

$640,000

Cash Flow: $160,000

Retail Military Tactical/Outdoor Clothing and Supplies

South Carolina

This established retail operation specializes in military tactical and outdoor clothing and supplies, serving the growing adventure sports and preparedness market. The business has maintained...

$210,000

Cash Flow: $54,000

Established 16-Year Legacy Seafood & Specialty Market

Camden, SC

TURNKEY SEAFOOD & SPECIALTY MARKET WITH 16-YEAR LOCAL LEGACY This established boutique seafood and specialty market represents a rare opportunity to acquire Camden, South Carolina's premier...

$235,000

Cash Flow: $126,831

Profitable Luxury Specialty Store in the Heart of Downtown Charleston

Charleston, SC

This is a rare opportunity to acquire one of Charleston’s most beloved and enduring specialty retail businesses, with a history spanning multiple generations. Known for refined Southern charm and...

$375,000

Cash Flow: $118,684

Liquor Store. Very Busy Area

Greenville County, SC

In South Carolinas busiest street...

$400,000

FranchiseMonkee's Franchising

Available in South Carolina

Buy your own Monkee’s®! A ladies boutique beyond your “girlie” imagination, known for the ultimate selection of shoes, clothing and accessories.

$100,000

$100,000

Southern Charm Bridal Shop & Tuxedo Rentals

Hilton Head Island, SC

Transform Your Entrepreneurial Dreams Into Wedding Magic Step into immediate profitability with this turnkey bridal and formalwear empire that delivers everything you need to dominate the lucrative...

$230,000

EBITDA: $85,156

"Reduced" Furniture and Consignment Store

Hilton Head Island, SC

REDUCED... Owner needs to sell health Problems... Long time Furniture and Consignment Store, Great location on Hilton Head Island, over $350,000 in stock items for sale, very profitable, long-term...

$395,000

Cash Flow: $200,000

Well-established Coastal Florist for Sale

Georgetown County, SC

************NOT SBA ELIGIBLE / CASH HEAVY / ALL NUMBERS CAN BE PROVED********** This represents a rare opportunity to acquire a highly profitable, full-service floral retailer and design studio...

$100,000

Cash Flow: $89,294

Charleston Vape Store Monthly Sales $60k+ and Inventory Included

Charleston, SC

This Vape Store will go quickly. If you want it, come and get it. The Vape Industry is extremely Popular and is showing no signs of slowing down. This store is located in a Busy Charleston Area and...

$600,000

Outdoor & Casual Clothing Retailer

South Carolina

The Company is a reputable retail business with a loyal customer base, extensive inventory, and a high-visibility South Carolina location. The store specializes in outdoor and casual apparel,...

$1,990,000

Cash Flow: $503,431

Well Established Scandinavian Modern Style Home Furniture Store

Charleston, SC

WELL ESTABLISHED SCANDINAVIAN MODERN FURNITURE STORE - CHARLESTON, SC This turnkey furniture and home decor business represents a rare opportunity to acquire a professionally branded, well-established...

$899,000

Cash Flow: $185,000

Hemp Healthcare Business with Greenhouse & eCommerce

Columbia, SC

Overview Step into ownership of a thriving, fourth-generation hemp business that blends tradition with innovation. This Hemp Company has a trusted name in South Carolina, known for its commitment to...

$180,700

Vending business and location

Greenville, SC

ESTABLISHED ICE AND WATER VENDING BUSINESS - GREENVILLE, SC This turnkey ice and water vending operation features the premium Everest VX ice vending machine, recognized for its superior reliability...

$40,000

Cash Flow: $26,000

Confidential Liquor Store for Sale: Bamberg County, SC

Bamberg County, SC

A unique opportunity awaits a motivated buyer to acquire a liquor store in a quiet, picturesque town in the heart of the South Carolina Lowcountry. The business is a staple of the community and the...

$99,000

Cash Flow: $15,573

Upscale Mobile Custom Suits/Blazers Biz w/70% Net Profits!

Greenville, SC

Imagine running your own upscale mobile tailoring business where you're bringing premium custom clothing directly to high-end clients in the thriving Greenville-Spartanburg area. This isn't just any...

$54,000

FranchiseMinuteman Press Business Services

Available Nationwide

Minuteman Press is the world's largest & #1 rated digital printing and graphics franchise. With our state of the art technology, proven marketing programs and over 25 regional support offices, we have been able to take quality people from all walks of life and provide them with the opportunity to secure their financial future.

$50,000

$50,000

Mount Pleasant SC Women's Boutique For Sale

Mount Pleasant, SC

Nestled in a fantastic location in a scenic southeastern coastal town, this women’s boutique offers a curated collection of timeless, elegant fashion. Specializing in versatile dresses—maxis, minis,...

$90,000

Cash Flow: $15,031

Flooring Sales and Installation $1.4M Sales | Western Horry County

Horry County, SC

This legacy business had a fantastic year in 2025 and continues to generate solid sales and earnings with experienced staff and growing trends in place. BUSINESS IS UP!! Pushing $1.4M in sales last...

$329,000

Cash Flow: $180,000

Turnkey Opportunity: Thriving Liquor Store

Beaufort County, SC

The offering is a locally owned and operated retail liquor store that has been serving the Bluffton community for over 15 years. Known for its wide selection of liquor and carefully curated wine...

$123,900

Cash Flow: $66,000

Specialty Home Furnishing Shop Offering Unique Opportunity

Mount Pleasant, SC

We are offering a unique opportunity to take ownership of a one-of-a-kind specialty furniture retailer with a strong 25+ year presence in the Charleston, SC market. Known for its extensive inventory...

$60,000

Cash Flow: $71,426

Charleston, SC- Automotive Repair Franchise

Charleston, SC

Simple, repeatable operations that generate robust cash flow, boasting an impressive 70%+ repeat customer rate. Situated in a prime retail-dense trade area, this franchise is strategically positioned...

$1,500,000

Cash Flow: $600,000

Franchise810 Entertainment

Available Nationwide

810 is an upscale bowling, entertainment and dining experience where friends and family gather to be social, friendly competition and great food.

$650,000

$650,000

Asset SaleMobile Golf Service Franchise — Side Hustle or 3-Day Workweek High ROI

Charleston, SC

This is the only mobile golf-grip service franchise of its kind — a first-to-market concept operating in a booming, $100B+ global golf industry. Designed for entrepreneurs seeking a flexible,...

$64,000

Asset Sale

$64,000

Start-upHigh Margin E-Cig/Nicotine & Custom Vending Machines!

Looking for your next side hustle? Sunstate Vending is a U.S. based premium vending provider looking to break the barrier of entry into entrepreneurship. We specialize in high end software driven...

$15,000

$18.5M Revenue Specialty Pharmacy Platform – South Carolina

$15,000

Columbia, SC

Business Overview Confidential, off-market specialty pharmacy platform headquartered in South Carolina. The company operates as a specialty-focused model with no retail or LTC exposure. Founded in...

$7,000,000

EBITDA: $1,000,000

High-End, Resort-Style Women's Boutiques in Multiple Prime Locations.

North Myrtle Beach, SC

Business Overview Multiple locations included in this listing. Established 7-year boutique located in a high-traffic, desirable area. Known for its upscale merchandise mix, exclusive product lines,...

$325,000

Established Turn Key DME Retail with Service and Rental Incomes

Taylors, SC

Retail Durable Medical Equipment specializing in Scooters, Powe Chairs, Wheel Chairs, Knee Scooters, Rollators, bathroom equipment, ramps, including service, rentals, and repairs....

$125,000

Cash Flow: $52,000

Chris Calcagno

Covenant Health Advisors

Serving Greenville County, SC

Covenant Health Advisors is exclusively Healthcare Services focused. We help business owners market and sell their companies, helping them to achieve the best valuation in todays market. We also represent a large pool of vetted buyers looking to acquire within Healthcare Services. We work nationally.

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Lexington, SC - Convenience Store, Fuel and Liquor Store

Lexington, SC

Convenience Store, Liquor Store & Gas Station – Business for Sale Well-established convenience store with liquor sales and fuel, located in Lexington, South Carolina (Lexington County). This is a...

$29,000

$750K Revenue Upstate Boutique $150K SDE

South Carolina

Step into ownership of an elegantly established ladies’ clothing boutique generating over $750,000 in annual revenue with $150,000 in profit. The curated, ready-to-sell inventory is additional @...

$370,000

Cash Flow: $154,054

Furniture & Furnishing Store In The Hilton Head Is, Bluffton Market

Beaufort County, SC

Established Furniture & Furnishing Store with annual Sales Revenue above $1,500,000. Existing furniture inventory with a value exceeding $1,000,000 included in the sale....

$3,000,000

High-End Women’s Fashion Boutique – Charleston County

Berkeley County, SC

Excellent opportunity to acquire a well-established, highly profitable women’s boutique in a prime Charleston County location. Situated in an affluent area with strong foot traffic, this boutique...

$125,000

Cash Flow: $300,000

Liquor Store - Great Location with High Traffic

Greenville, SC

Great liquor store for sale! A well-established liquor store in the thriving Greenville, SC area is now available for acquisition. This profitable business offers a diverse selection of wines and...

$220,000

Cash Flow: $40,857

FranchiseChildren's Orchard®

Available Nationwide

It is resale reimagined. Children’s Orchard sells gently used name-brand kid’s clothing, shoes, and accessories for up to 70% off retail prices. If you have been feeling the need for a professional change that offers flexibility, growth potential, and personal fulfillment, Children’s Orchard franchise ownership might be the path you have been searching for. The resale industry is booming, and franchising has real advantages, but the best part is the process is already nailed down for you.

$100,000

Thriving Vending Business with Room For Growth

Myrtle Beach, SC

This vending machine business specializes in healthy snacks and beverages. Strategically located in high-traffic areas such as gyms, hospitals, schools, and offices, this business has a proven track...

$147,950

Cash Flow: $140,381

Established Boutique Jewelery store

Spartanburg, SC

This is a locally-trusted jewelry retailer located in downtown Spartanburg, South Carolina, known for its personalized service, quality craftsmanship, and broad selection of fine jewelry including...

$120,000

Cash Flow: $50,000

Imprint and Personalized Products

Myrtle Beach, SC

A lifestyle brand that offers a variety of personalized and monogramed products, including every day and seasonable items. This well-seasoned online wholesale and retail business that designs and...

$1,500,000

Cash Flow: $400,000

Specialty Apparel and Accessories

South Carolina

A world of timeless style and rugged sophistication for an established specialty apparel business of almost 50 years. In many ways this company has moved an entire industry forward, designing and...

$1,500,000

Cash Flow: $200,000

Profitable Confectionery Retailer with E-Comm & B2B Growth

Charleston County, SC

This established confectionery business operates a brick-and-mortar retail store with in-house production and a growing e-commerce platform, specializing in premium, homemade sweets. It offers a...

$325,000

Cash Flow: $100,000

FranchiseWOOPS! Macaron & Corporate Gifting

Available in South Carolina

Sweeten life’s moments with WOOPS! – a vibrant macaron franchise bringing joy, color, and flavor to the $242B gifting world!

$50,000